ANTECH SOLUTIONS · RESOLVE

Keep your mobile phase working.

Recover suitable flow from isocratic HPLC runs. Put it back to use, with less fresh solvent to prepare and less liquid waste to manage.

Watch ReSolve in action ↗Arrange a demonstration

HPLC mobile-phase recovery · Application support from Antech

Download the PMBrc white paper ↓

Laboratory analyst using the ReSolve touchscreen on an HPLC system — LESS FRESH SOLVENT. More use from every suitable preparation.

THE 67-SECOND STORY

See ReSolve in action.

Discover the recovery principle, the equipment and the opportunity to reduce everyday solvent handling.

Watch the introduction on YouTube ↗

Introducing ReSolve · Antech Ireland · 1 minute 7 seconds. Recovery and reuse depend on the method.

THE RECOVERY PRINCIPLE

Recover the baseline.
Divert the peaks.

ReSolve uses the detector signal to control a valve after the detector. Selected flow returns for reuse; detected peak fractions go to waste.

Between peaks: return flow

Eligible baseline flow returns to the reservoir within the approved reuse method.

Peak detected: divert to waste

Peak fractions go to waste, including the configured timing margin.

Detector-to-valve delay and peak margins are configured for the method. ReSolve routes the liquid; it does not purify it.

ReSolve schematic showing reservoir, pump, injector, column, detector and diversion valve, with teal return flow, orange waste flow and dashed control signals — Simplified flow and control schematic: return eligible baseline flow and divert detected peak fractions. Click to enlarge.

THE EVERYDAY LABORATORY BENEFIT

Less fresh solvent.
Less liquid waste.

Make suitable repeated methods work harder for your laboratory.

More use from each preparation

Return eligible mobile phase to the working reservoir and reduce the fresh volume needed for suitable repeated methods.

Less liquid sent to disposal

Separate peak fractions from recoverable flow and measure the reduction in waste across the complete workflow.

Fewer bottle changes

Extend the use of a suitable preparation, reducing reservoir refills and waste-bottle handling.

Include top-ups, purging, cleaning, replacement and eventual disposal in your assessment. Recovery percentage and total cost saving are different measures.

CONTROL YOU CAN SEE

A clear view
of every run.

The 4-inch touchscreen shows the detector trace and operating state. Injection logs and audit trails keep recovery events available for review.

Live trace: Follow the detector signal and return/waste status.
Method settings: Configure peak detection and the timing of diversion.
Reviewable records: Retrieve injection reports and audit trails for the approved workflow.

Discuss your HPLC setup ↗

ReSolve controller and valve installed alongside HPLC equipment — Controller and valve mounted alongside the chromatograph.

ReSolve touchscreen with detector trace and recovery status — Touchscreen example. Displayed values are not recommended method settings.

Example ReSolve injection report with recovery and waste events — Example injection report. Its recovery figures belong to the displayed example.

Independent performance evaluation
PMBrc · South East Technological University

94.5%

reported recovery

In each of two tested sequences

THE EVIDENCE BEHIND RESOLVE

See the results.
Read the white paper.

Explore the method, recovery data and chromatograms in PMBrc’s independent performance evaluation of ReSolve, commissioned by Antech Solutions.

Download the white paper

PDF · 24 pages · PMBrc / SETU
No form required. Open the full report and save your copy.

Recovery measured alongside analytical performance.

Two sequences each contained 96 injections; the second used mobile phase recovered from the first. The study reported comparable observed chromatographic metrics with fresh and recovered starting mobile phase.

2 × 96 injections1 mL/min isocratic flow230 nm UV detection

Paracetamol/ibuprofen method; buffer, acetonitrile and methanol at 75:24.5:0.5 v/v/v. PMBrc / SETU, final report Rev 4.0, 22 July 2026. Results apply to the tested sequences; they do not establish a universal recovery rate, formal statistical equivalence or unlimited reuse.

MATCH THE PRODUCT TO THE METHOD

Plan a practical installation.

Start with a suitable isocratic method, the actual detector output and a representative chromatogram.

Which methods should we evaluate first?

Prioritise repeated isocratic methods with a stable mobile phase and useful baseline intervals. Review the full sample matrix, detector response and permitted reuse period. The study does not establish suitability for gradient HPLC or SFC.

What should we send Antech?

Tell us your HPLC system and detector, the mobile-phase composition and flow rate, your sample matrix, a representative chromatogram and the number of runs you perform. We will help you plan an evaluation for your workflow.

ReSolve at a glance

Detector input: −1.000 to +2.000 V
Trigger: Autosampler injection-start signal
Display: 4-inch touchscreen
Flow diversion: Valve after the detector outlet
Fluid connections: 1/16-inch tubing; 1/4-28 ports
Valve materials: Teflon; PEEK option
Power supply: 100–240 V AC
Operating temperature: 10–40 °C

EXPLORE THE EVIDENCE

A closer look at ReSolve.

See the study behind the results, then explore what ReSolve could mean for your laboratory.

Chromatograms from page 10 of the PMBrc report

Cover of the PMBrc ReSolve validation white paper

Look inside the white paper ↗

PMBrc / SETU · INDEPENDENT PERFORMANCE EVALUATION

Real methods.
Recovery data.
Chromatograms.

Get the full picture of how ReSolve was evaluated. The 24-page white paper brings together the experimental method, measured recovery and chromatographic results.